Rather than turn criminal aliens to ICE authorities as requested, sanctuary cities disregard such requests and frequently simply discharge the illegals. CIS noted that many of these released were release despite multiple detainer requests. Almost all, 5,132, had past police records, like Sanchez. Of these, 2,984 had a prior felony charge or conviction. In addition, 1,867 offenders who were released had been re-arrested, accumulated 7,491 new charges including child sex abuse, Vaughn’s report noted.Food and Drug Administration has approved for filing the Company's New Medication Application for its ghrelin agonist, macimorelin acetate, in Adult Growth Hormone Insufficiency . The acceptance for submitting of the NDA signifies the FDA has established that the application is sufficiently complete allowing a substantive review. The application form will be subject to a regular review and will have a Prescription Medication User Fee Work day of November 5, 2014. The PDUFA date may be the goal date for the FDA to complete its overview of the NDA. David Dodd, President and CEO of Aeterna Zentaris, commented, ‘The FDA's acceptance of this NDA submission is another significant milestone in our technique to commercialize macimorelin acetate while the first approved oral item for AGHD evaluation.