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Acupuncture at Waiguan influences activation of mind regions in individuals with ischemic stroke Both acupuncture at Waiguan and sham acupuncture can activate/deactivate several mind regions in patients with ischemic stroke, but there are some difference in Brodmann areas 4, 6, 8, Brodmann areas 7, 39, 40, Brodmann areas 18, 19, 22 and Brodmann areas 13, 24, 32, 28. Most studies addressing the specificity of meridians and acupuncture points have focused primarily on the various neural ramifications of acupuncture at different points in healthy people.