Agena Bioscience expands ultrasensitive somatic mutation detection technology Agena Bioscience.

Dr. Nishio's research indicates that detecting in blood plasma a low-level mutation such as for example T790M, which occurs at a frequency below 0 sometimes.5 percent, may indicate future tumor regrowth and the need to assess an alternative treatment plan,’ stated Lillig. The UltraSEEK technique employs a PCR response accompanied by an extension response. The extension response utilizes a single mutation-specific chain terminator labeled with a moiety for solid stage capture. The method can be conducted on 384-well and 96-well plates, the smaller which accommodates to 24 samples to facilitate studies comparing multiple sample types up. The complete workflow for the UltraSEEK panels, from extracted sample DNA to the final mutation report, could be completed in a single day.In a study just published in BMC Tumor, researchers found that a diet of flaxseed given to mice not only protects lung tissues before exposure to radiation, but can significantly reduce damage after exposure occurs also. ‘There are only a handful of potential mitigators of radiation impact, and none of them is ready for the clinic nearly,’ says the principal investigator Melpo Christofidou-Solomidou, PhD, research associate professor of Medication, Pulmonary, Allergy and Crucial Care Division. ‘Our current study demonstrates that dietary flaxseed, known for its solid antioxidant and anti-inflammatory properties already, works as both a mitigator and protector against radiation pneumonopathy.’ In several separate experiments, the experts fed one group of mice a diet plan supplemented with 10 % flaxseed, either three weeks before a dose of X-ray radiation to the thorax or two, four, or six weeks after radiation exposure.