Anno Diegeler.

We allowed for the exclusion of individuals after randomization therefore. This ultimately resulted in an imbalanced exclusion of individuals assigned to off-pump CABG. The similarity of the outcomes attained in the per-protocol evaluation argues against a significant bias. In conclusion, our randomized trial of off-pump versus on-pump CABG in elderly patients did not show a significant advantage of either operative approach with respect to clinical outcomes at 30 days or 1 year.. Anno Diegeler, M.D., Ph.D.D., Ph.D., Utz Kappert, M.D., Ph.D., Martin Breuer, M.D.D., Ph.D., Adrian Ursulescu, M.D., Ardawan Rastan, M.D., Ph.D., David Holzhey, M.D., Ph.D., Hendrik Treede, M.D., Ph.D.D., Ph.D., Philippe Veeckmann, M.D., Amjad Asfoor, M.D., Wilko Reents, M.D., Michael Zacher, M.D., and Michael Hilker, M.D., Ph.D.In this group, the SMR for colorectal cancer tumor was 1.10 , which is slightly higher than the SMR for the whole cohort . Nevertheless, as in any longitudinal study, the downside of much longer follow-up can be that individuals were included in the past, today and the interventions then may differ from the ones offered. Thus, the evaluation of two intervals of adenoma removal is definitely of value, since it might reveal that in the modern era of colonoscopic removal of adenomas, the risk of loss of life from colorectal malignancy is significantly smaller sized than in earlier intervals.