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Moreover, human growth hormone builds up muscle mass with the forming of new muscle tissue cells. This is different from hypertrophy, which is the increase in volume of existing cells. Hgh also reduces body fat through lipolysis, which is the reduction of adipose tissue or fat tissue in the physical body. On top of all of these affects, hgh increases protein synthesis. This protein synthesis stimulates growth, but not of muscle tissue cells and bone cells just, this total effects in the enlargement of all internal organs apart from the brain. Hgh deficiency could cause different physical problems at various ages considerably. In children, having less appropriate amounts of hgh can lead to short stature and failure of growth.