Previous studies have shown that immune cells in the brain called the microglia reactive reactive with age. When the older rats in the study involve a bacterial infection, these immune cells are inflammatory molecules called cytokines released in an exaggerated and prolonged way. – In the present study we found that low levels of voluntary exercise prevented the priming of microglia, the exaggerated inflammation in the brain, and the decrease of growth factors, Barrientos said.
Proprietary projects three programs on the development of new therapies for diseases of the central nervous system, Evotec has three programs in clinical development. EVT 201, a partial positive allosteric modulator of the GABAA receptor complex for the treatment of insomnia, EVT 101 a subtype selective NMDA receptor antagonist for the treatment of Alzheimer’s disease and / or pain, and EVT 302, a MAO-B inhibitor in development for smoking cessation. Strategies research programs focus on the purinergic receptors, P2X3 and P2X7, for the potential treatment of pain and inflammatory diseases. In addition, Evotec global collaboration and license agreement with Pfizer to research, development and commercialization of small molecule vanilloid receptor antagonists. For further information please go to..Gazit new research at protofibrils has yet in its early stages, however it shows the need a shift of focus by breaking up mature fibrillae deposit inhibition earlier stage of the protofibril formation. His group has developed several potential inhibitor molecules and are testing their potency.
Sir Liam Donaldson said:’In our fight treat tuberculosis, the disease is won again the upper hand, We are need to go back public health foundations identify the group at an early stage high-risk use effective treatment for you and. ,, the illness be pursue show all important enforcement measures Experience who that the march that the march the TB can be stopped.. ‘This is a very important issue and I have discussed an informal with their counterparts European. I did purpose that we are. The first country who how a comprehensive agenda, and I am so thankful to COM have concluded for make this major labor ‘.
– research for better medications and vaccines.